Sunday, February 16, 2020

Stakeholder Theory Essay Example | Topics and Well Written Essays - 500 words

Stakeholder Theory - Essay Example Stakeholders include shareholders, employees, suppliers, customers, and the communities in which the firm operates-a collection that Freeman terms the "big five." The very purpose of the firm, according to this view, is to serve and coordinate the interests of its various stakeholders. It is the moral obligation of the firm's managers to strike an appropriate balance among the five interests in directing the activities of the firm. This understanding of the firm's purpose and its management's obligations diverges sharply from the understanding advanced in the shareholder theory of the firm. According to shareholder theorists such as Nobel laureate economist Milton Friedman, managers ought to serve the interests of the firm's owners, the shareholders. Social obligations of the firm are limited to making good on contracts, obeying the law, and adhering to ordinary moral expectations. In short, obligations to nonshareholders stand as side constraints on the pursuit of shareholder interests. This is the view that informs American corporate law and that Friedman defends in his 1970 New York Times Magazine essay, "The Social Responsibility of Business Is to Increase Its Profits." (Thomas. J. Donaldson, 1994) Stakeholder theory seeks to overthrow the shareholder orientation of the firm.

Sunday, February 2, 2020

Hot Melt Extrusion Essay Example | Topics and Well Written Essays - 750 words

Hot Melt Extrusion - Essay Example HME technique does not require time consuming drying step and compressing step; and therefore, the processing steps are significantly reduced. Due to fewer unit operations involved in HME operation, production time is greatly enhanced. During the HME process, the polymer-melt itself act as a thermal binder. HME eliminates problems arising from poorly compactible materials. An extruded rod obtained from HME procedure can be directly incorporated into tablets after cutting. Uniform dispersion of fine particles is obtained due to vigorous mixing and agitation conditions of HME operation. The energy requirements in HME process are low as compared to high shear granulation. The HME process requires lower investment for equipment as against other processes. HME technique also provides new strategies to increase dissolution rates for sparingly water soluble drugs, enhance bioavailability of the active ingredient, improve content uniformity of dosage formulation, modify drug release, and als o helps to mask the unpleasant taste of the drug (Repka et al. 1043; Crowley et al. 909). A single- or twin-screw extruders are used for HME process. The extruder is composed of a feeding hopper, barrels, single or twin screws, die, screw-driving unit, heating/cooling device for the barrels, conveyer belt to cool down the product, and solvent delivery pump. The monitoring devices on the equipment include temperature gauges, a screw-speed controller, an extrusion torque monitor and pressure gauges. During the HME process, first a dry powder blend of drug, polymer, and other adjuvants/additives is prepared. Then, this soild mixture is fed into the feeding section of the extruder. The material is transferred to the melting section. The heat is applied to the material in the melting section to form the polymer-melt. This molten mass is transferred in the metering section which is then